|Long before he was huge (Boston Globe)|
1) New England quarterback Tom Brady has never played the 49ers in San Francisco.
2) Tom Brady, on the short list of all-time greatest quarterbacks, was born in San Mateo and attended Junipero Serra High. (Serra is also the high school for Barry Bonds, one of baseball's greatest and most controversial players.)
3) The 49ers are going nowhere, Expect to see some cheering for the hometown hero, especially since, at 39, this is likely to be Tom Brady's last game in SF as well as his first.
[Update - 11/20: 1) Tom Brady threw four touchdown passes in the Patriots' 30-17 victory. 2) Eric Reid sustained a season-ending biceps injury. 3) New England fans were plentiful at Levi Stadium.]