Saturday, February 04, 2023

Light Me Up Some Loco Weed

(Image from Veriheal)
There's some evidence that cannabis can help late-stage Alzheimer's patients: [bold added]
Approximately 6.5 million Americans, or 1 in 9 people aged 65 and older, are living with Alzheimer’s dementia. Agitation, aggression, wandering, delusions, hallucinations, mood disturbances and repetitive vocalizations are very common symptoms as the disease progresses. There are no FDA-approved pharmaceuticals to treat the condition, so when behavioral techniques fail, doctors use off-label medications such as antidepressants, mood stabilizers or antipsychotics. Antipsychotics become necessary when the patient risks harming themselves or others due to the severity of the agitation, but they are only modestly effective and carry a black box warning for increasing the risk of death in this population.

Recent research suggests that cannabis may help to relieve agitation by regulating neurotransmitters, reducing brain inflammation and improving circadian rhythm disturbances seen in dementia. It is thought that cannabis binds with receptors located in the same regions of the brain implicated in dementia agitation. A study in mice further found that THC (the major psychoactive component in cannabis) may prevent the harmful plaques associated with Alzheimer’s from accumulating between neurons. Further research may yet determine whether cannabis has the potential not only to treat Alzheimer’s symptoms but to halt the disease’s progression.
I never touched the stuff when younger, but trust the science. If I get Alzheimer's agitation, my caregivers are authorized to light me up some loco weed.

No comments: